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Addgene inc aip12610 paav aie0780m minbg syfp2 wpre3 bghpa
(A) Bulk ATAC-seq open chromatin regions in cortex and striatum of humans, macaques, rats, and mice at conserved orthologs of five enhancer loci. (B) Conservation of striatal enhancer specificity in vivo in mouse and rat brain. Sagittal brain sections with native <t>SYFP2</t> (green) and DAPI (blue). (C–H) Stereotaxic injection of <t>AiE0780m</t> driving SYFP2 expression ( <t>AiP12610</t> ) into macaque caudate and putamen. (C) Coronal section of striatum injection site with propidium iodide (red), DAPI (blue), and native SYFP2 (green). (D) Example RNAscope images from putamen injection site. Yellow circles, SYFP+DRD1+PPP1R1B+ cells. (E–H) Coronal sections posterior to the injection site showing axon terminal labeling in GPi and SNr. See also .
Aip12610 Paav Aie0780m Minbg Syfp2 Wpre3 Bghpa, supplied by Addgene inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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(A) Bulk ATAC-seq open chromatin regions in cortex and striatum of humans, macaques, rats, and mice at conserved orthologs of five enhancer loci. (B) Conservation of striatal enhancer specificity in vivo in mouse and rat brain. Sagittal brain sections with native SYFP2 (green) and DAPI (blue). (C–H) Stereotaxic injection of AiE0780m driving SYFP2 expression ( AiP12610 ) into macaque caudate and putamen. (C) Coronal section of striatum injection site with propidium iodide (red), DAPI (blue), and native SYFP2 (green). (D) Example RNAscope images from putamen injection site. Yellow circles, SYFP+DRD1+PPP1R1B+ cells. (E–H) Coronal sections posterior to the injection site showing axon terminal labeling in GPi and SNr. See also .

Journal: Neuron

Article Title: Enhancer AAV toolbox for accessing and perturbing striatal cell types and circuits

doi: 10.1016/j.neuron.2025.04.035

Figure Lengend Snippet: (A) Bulk ATAC-seq open chromatin regions in cortex and striatum of humans, macaques, rats, and mice at conserved orthologs of five enhancer loci. (B) Conservation of striatal enhancer specificity in vivo in mouse and rat brain. Sagittal brain sections with native SYFP2 (green) and DAPI (blue). (C–H) Stereotaxic injection of AiE0780m driving SYFP2 expression ( AiP12610 ) into macaque caudate and putamen. (C) Coronal section of striatum injection site with propidium iodide (red), DAPI (blue), and native SYFP2 (green). (D) Example RNAscope images from putamen injection site. Yellow circles, SYFP+DRD1+PPP1R1B+ cells. (E–H) Coronal sections posterior to the injection site showing axon terminal labeling in GPi and SNr. See also .

Article Snippet: AiP12610 - pAAV-AiE0780m-minBG-SYFP2-WPRE3-BGHpA (Alias: CN2610) , Addgene; this study , Cat#191737.

Techniques: In Vivo, Injection, Expressing, RNAscope, Labeling